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Symbol
Name
ID
Plau
plasminogen activator, urokinase
MGI:97611
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
heart inflammation
impaired macrophage chemotaxis
decreased T cell proliferation
impaired neutrophil phagocytosis
increased neutrophil cell number
increased lymphocyte cell number
increased monocyte cell number
abnormal neutrophil physiology
impaired granulocyte bactericidal activity
abnormal macrophage physiology
abnormal acute phase protein level
abnormal cytokine level
abnormal cell-mediated immunity
increased interleukin-1 beta secretion
increased tumor necrosis factor secretion
decreased susceptibility to induced arthritis
chronic inflammation
decreased inflammatory response
increased inflammatory response
liver inflammation
trachea inflammation
increased susceptibility to fungal infection
increased susceptibility to parasitic infection
Availability Mouse Genotype
Plautm1.1Bug/Plautm1.1Bug
Plautm1b(EUCOMM)Wtsi/Plautm1b(EUCOMM)Wtsi
Plautm1Mlg/Plautm1Mlg
Tg(MSR1-Plau)1Ddi/0
Tg(Mup3-Plau)350-2Eps/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory